Peter A Crooks Selected Research

LC-1 compound

1/2018	Actinomycin-D and dimethylamino-parthenolide synergism in treating human pancreatic cancer cells.
7/2012	Dimethylamino parthenolide enhances the inhibitory effects of gemcitabine in human pancreatic cancer cells.
10/2008	Effect of celecoxib and the novel anti-cancer agent, dimethylamino-parthenolide, in a developmental model of pancreatic cancer.
12/2007	An orally bioavailable parthenolide analog selectively eradicates acute myelogenous leukemia stem and progenitor cells.

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Peter A Crooks Research Topics

Disease

43	Neoplasms (Cancer) 11/2021 - 04/2004
11	Pain (Aches) 01/2021 - 10/2008
10	Tobacco Use Disorder (Nicotine Dependence) 12/2018 - 10/2006
10	Acute Myeloid Leukemia (Acute Myelogenous Leukemia) 01/2017 - 12/2007
8	Pancreatic Neoplasms (Pancreatic Cancer) 01/2018 - 02/2003
6	Breast Neoplasms (Breast Cancer) 01/2021 - 01/2010
5	Hyperalgesia 01/2018 - 10/2008
5	Leukemia 01/2018 - 09/2004
5	Alcoholism (Alcohol Abuse) 07/2010 - 06/2004
4	Prostatic Neoplasms (Prostate Cancer) 11/2017 - 09/2007
4	Chronic Pain 04/2013 - 10/2008
4	Neuralgia (Stump Neuralgia) 09/2012 - 10/2008
4	Peripheral Nervous System Diseases (PNS Diseases) 09/2012 - 10/2008
3	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 01/2019
3	Infections 01/2021 - 12/2015
3	Lung Neoplasms (Lung Cancer) 01/2018 - 11/2007
2	Glioblastoma (Glioblastoma Multiforme) 10/2021 - 01/2019
2	Cachexia 01/2021 - 12/2017
2	Obesity 10/2020 - 04/2013
2	Cardiotoxicity 11/2019 - 01/2018
2	Melanoma (Melanoma, Malignant) 01/2018 - 01/2010
2	Carcinogenesis 04/2013 - 11/2007
2	Neoplasm Metastasis (Metastasis) 04/2013 - 10/2008
2	Adenocarcinoma 04/2013 - 01/2013
2	Hyperthermia 12/2007 - 01/2007
2	Acute Pain 03/2006 - 03/2006
1	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2021
1	Fibromyalgia (Fibrositis) 01/2021

Drug/Important Bio-Agent (IBA)

14	Pharmaceutical PreparationsIBA 10/2019 - 03/2006
12	parthenolideIBA 01/2018 - 06/2007
8	Nicotine FDA Link 10/2015 - 03/2007
7	NF-kappa B (NF-kB)IBA 10/2021 - 06/2007
6	Morphine (MS Contin)FDA LinkGeneric 01/2021 - 10/2008
6	Proteins (Proteins, Gene)FDA Link 01/2021 - 06/2007
6	melampomagnolide BIBA 09/2018 - 08/2014
6	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 09/2012 - 10/2007
5	Analgesics (Analgesic Drugs)IBA 01/2021 - 01/2010
5	ResveratrolIBA 01/2019 - 05/2015
5	DNA (Deoxyribonucleic Acid)IBA 09/2018 - 09/2007
5	TubulinIBA 01/2018 - 03/2015
5	Formaldehyde (Formol)FDA Link 11/2011 - 10/2008
5	Naltrexone (ReVia)FDA LinkGeneric 07/2010 - 06/2004
4	morphine-6-O-sulfateIBA 01/2021 - 12/2010
4	Antineoplastic Agents (Antineoplastics)IBA 01/2018 - 04/2004
4	LC-1 compoundIBA 01/2018 - 12/2007
4	AntioxidantsIBA 01/2018 - 09/2007
3	Peptides (Polypeptides)IBA 01/2021 - 04/2011
3	CannabinoidsIBA 10/2020 - 04/2013
3	EnzymesIBA 01/2019 - 09/2007
3	3,4,5,4'-tetramethoxystilbeneIBA 01/2018 - 07/2015
3	Biomarkers (Surrogate Marker)IBA 12/2017 - 12/2007
3	Transcription Factors (Transcription Factor)IBA 11/2017 - 01/2013
3	indoleIBA 08/2017 - 05/2010
3	Opioid Analgesics (Opioids)IBA 11/2016 - 01/2010
3	Gemcitabine FDA Link 04/2013 - 07/2012
3	Oxycodone (Oxycontin)FDA LinkGeneric 12/2010 - 03/2006
3	nornicotineIBA 01/2010 - 03/2007
2	CarbamatesIBA 11/2021 - 08/2014
2	Vancomycin FDA LinkGeneric 01/2021 - 12/2015
2	EstersIBA 01/2021 - 08/2017
2	Anti-Bacterial Agents (Antibiotics)IBA 01/2021 - 01/2018
2	Phenobarbital (Luminal)FDA Link 01/2021 - 01/2016
2	Amyloid (Amyloid Fibrils)IBA 01/2021 - 01/2019
2	DNA-Directed DNA Polymerase (Polymerases, DNA)IBA 01/2019 - 01/2018
2	CytokinesIBA 01/2019 - 12/2017
2	TriazolesIBA 09/2018 - 08/2015
2	StilbenesIBA 01/2018 - 05/2015
2	LactonesIBA 01/2018 - 04/2010
2	SesquiterpenesIBA 01/2018 - 04/2010
2	Opioid Receptors (Opioid Receptor)IBA 01/2018 - 01/2017
2	Glutathione (Reduced Glutathione)IBA 01/2018 - 11/2013
2	Radiation-Sensitizing AgentsIBA 11/2017 - 07/2013
2	benzofuranIBA 07/2015 - 03/2015
2	combretastatinIBA 03/2015 - 07/2013
2	Reactive Oxygen Species (Oxygen Radicals)IBA 07/2013 - 04/2010
2	NADPH Oxidases (NAD(P)H oxidase)IBA 07/2013 - 04/2010
2	Cyclooxygenase 2 (Cyclooxygenase-2)IBA 01/2013 - 11/2007
2	Sulindac (Copal)FDA LinkGeneric 01/2013 - 06/2007
2	SaltsIBA 09/2012 - 12/2010
2	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 12/2010 - 09/2007
2	CarcinogensIBA 10/2008 - 11/2007
2	norketamineIBA 10/2008 - 10/2008
2	Celecoxib (Celebrex)FDA Link 10/2008 - 11/2007
2	CanavanineIBA 10/2003 - 02/2003
1	Tubulin ModulatorsIBA 10/2021
1	AcetylcholinesteraseIBA 01/2021
1	Chemokine CCL11IBA 01/2021
1	Sulfates (Sulfates, Inorganic)IBA 01/2021
1	2,3-trimethylene-4-quinazoloneIBA 01/2021
1	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2021
1	ButyrylcholinesteraseIBA 01/2021
1	Glycogen Synthase (Synthase I)IBA 10/2020

Therapy/Procedure

14	Therapeutics 01/2021 - 10/2003
7	Radiotherapy 01/2021 - 01/2007
7	Drug Therapy (Chemotherapy) 12/2018 - 10/2002
4	Analgesia 01/2017 - 01/2010
2	Self Administration (Administration, Self) 10/2015 - 03/2007
2	Chemoprevention 04/2013 - 10/2008
2	Combination Drug Therapy (Combination Chemotherapy) 10/2008 - 06/2007
1	Precision Medicine 10/2021